Color: Sabino is a color pattern in horses that results in irregularly-edged white patches of skin and hair, particularly on the face and feet, and may extend to the belly. Homozygous animals may be completely or nearly completely white.
Samples Accepted: Blood, Hair
Locus Information: SB
Test Information: This mutation test for the SB1 mutation is based on a single base change in the KIT gene. This mutation is incompletely dominant, meaning that animals with one copy will show the white pattern phenotype, while animals with two copies may be completely or nearly completely white. SB1 is common in various breeds, such as the Tennessee Walking Horse, Miniature Horses, Paint, Aztecas, Missouri Foxtrotters, Shetland, Spanish Mustangs, and Pony of the Americas. This is the most common mutation; however, it is possible for the sabino pattern to also be caused by other as-of-yet unknown mutations.
Brooks, S.A., Bailey, E.: Exon skipping in the KIT gene causes a Sabino spotting pattern in horses. Mamm Genome 16(11):893-902, 2005. Doi: 10.1007/s00335-005-2472-y.
Further information is available at the Online Mendelian Inheritance in Animals website.