- PATN1 is the first identified gene that modifies the Leopard Spotting Complex.
- Pattern-1 in combination with the Leopard Spotting Complex (LP) → at birth the foal will show an increased amount of white in its pattern (min. 60%).
- Pattern-1 without the Leopard Complex → no phenotypic effects on coat color.
- Horses may be carriers for this variant without showing any pattern themselves.
|n/n||Horses without the Leopard Complex and without PATN1 → usual coat color.
Horses with the Leopard Complex and without PATN1 → pattern with a usual amount of white (< 60%).
|LP/n + PATN1
||PATN1 with one copy of the Leopard Complex variant → pattern with an unusal amount of white (> 60%) at birth.
|LP/LP + PATN1
||PATN1 with two copies of the Leopard Complex variant → Leopard phenotype (full pattern).|
|→ Horses without the Leopard Complex may inherit the PATN1 variant even when they don’t show any pattern themselves. If bred to a horse with the Leopard Complex with a very low amount of white, offspring may show a surprisingly high amount of white if the PATN1 variant is passed on.|
Testinformation: This test detects the change of a single basepair in the non-coding region of the RFWD3 gene (PATN1 region).
Holl, H.M., Brooks, S.A., Archer, S., Brown, K., Malvick, J., Penedo, M.C.T., Bellone, R.R.: Variant in the RFWD3 gene associated with PATN1, a modifier of leopard complex spotting. Animal Genetics, 11/2015, Pubmed reference: 26568529. Doi: 10.1111/age.12375.
Test #: H217
Sample: Blood, Hair
Price: 35 € (net)
Time required: 7-10 days