Samples Accepted: Blood, Buccal Swabs
Locus Information: A locus: a-allele
The A locus has multiple alleles. Fawn/sable coded by the Ay-allele is dominant to the wildtype aw-allele. Black and tan (necessary for tri-color) is coded for by the at-allele. Recessive black is produced by the a-allele.
Test Information: This mutation test identifies only the a-allele of the A-locus: a single base change in the ASIP gene that is associated with the color recessive black.
Kerns, JA., Newton, J., Berryere, TG., Rubin, EM., Cheng, JF., Schmutz, SM., Barsh, GS.: Characterization of the dog Agouti gene and a nonagoutimutation in German Shepherd Dogs. Mamm Genome 15:798-808, 2004. Pubmed reference: 15520882. DOI: 10.1007/s00335-004-2377-1
Further information is available at the Online Mendelian Inheritance in Animals website.