Color: grizzle or domino
Samples Accepted: Blood, Buccal Swabs
Locus Information: E locus: Eg
The E locus has multiple alleles. The wildtype, E, results in a black animal, while Em codes for a melanistic (dark) mask, and Eg codes for grizzle (only in Salukis and Afghan hounds). The lightest color is coded for by the e allele.
Test Information: This mutation test identifies only the Eg allele of the E-locus: a single base change in the MC1R gene that is associated with the grizzle or domino patterns in Salukis and Afghan Hounds.
Dreger, DL., Schmutz, SM.: A new mutation in MC1R explains a coat color phenotype in 2 “Old” breeds: Saluki and Afghan Hound. J Hered: 2010. Pubmed reference: 20525767. DOI: 10.1093/jhered/esq061
Further information is available at the Online Mendelian Inheritance in Animals website.