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Color: White feet (also known as Gloves) are part of the distinctive look of the Birman cat breed.

Samples Accepted: Blood, Buccal Swabs

Locus Information: W

Test Information: This mutation test identifies a deletion/insertion (c.1035_1036delinsCA) mutation in the KIT gene. This trait is recessive, and the mutation is responsible for the distinctive white feet found in the Birman cat, and related breeds. This test will not detect other mutations that may cause white feet in some cats.

The mutation location was first reported in:
Lyons, LA.: Feline genetics: clinical applications and genetic testing. Top Companion Anim Med 25:203-12, 2010. Pubmed reference: 21147473. Doi: 10.1053/j.tcam.2010.09.002.

The mutation location has been confirmed by:
Montague MJ, Li G, Gandolfi B, Khan R, Aken BL, Searle SMJ, Minx P, Hillier LW, Koboldt DC, Davis BW, Driscoll CA, Barr CS, Blackistone K, Quilez J, Lorente-Galdos B, Marques-Bonet T, Alkan C, Thomas GWC, Hahn MW, Menotti-Raymond M, O’Brien SJ, Wilson RK, Lyons LA, Murphy WJ, Warren WC.: Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication PNAS 2014 111 (48) 17230-17235; published ahead of print November 10, 2014. Doi: 10.1073/pnas.1410083111.

Further information is available at the Online Mendelian Inheritance in Animals website.

Test #: C208

Cost: 35 € (excl. VAT)

Time: 7-10 days

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