Coat Phenotype: The Cornish Rex and German Rex are known for their curly, soft coats.
Samples Accepted: Blood, Buccal Swabs
Gene Information: LPAR6
Test Information: This mutation test identifies a 4 base deletion in exon 5 of the LPAR6 gene. This trait is recessive, and the Cornish Rex breeds are fixed (homozygous) for this mutation. The mutation also causes the curly hair in the German Rex breed.
Gandolfi, B., Alhaddad, H., Affolter, V.K., Brockman, J., Haggstrom, J., Joslin, S.E., Koehne, A.L., Mullikin, J.C., Outerbridge, C.A., Warren, W.C., Lyons, L.A.: To the Root of the Curl: A Signature of a Recent Selective Sweep Identifies a Mutation That Defines the Cornish Rex Cat Breed. PLoS One 8:e67105, 2013. Pubmed reference: 23826204. Doi: 10.1371/journal.pone.0067105.
Further information is available at the Online Mendelian Inheritance in Animals website.