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Phenotype: Coat length: Long vs Short hair

Samples Accepted: Blood, Buccal Swabs

Locus Information: FGF5

Test Information: Long hair has an autosomal recessive mode of inheritance, thus it is possible for short haired cats to be heterozygous for one of the four independent mutations in the FGF5 gene causative for long hair. Long haired cats can be homozygous for one of the mutations, or be compound heterozygous (having two different mutations).

Mutation 1, a single base insertion in FGF5, has only been found in Ragdoll cats.

Mutation 2, a single base change in FGF5, has only been found in Norwegian Forest cats.

Mutation 3, a single base deletion in FGF5, has been found in both Ragdoll cats and Maine Coon cats.

Mutation 4 , a single base change in FGF5, has been found in all breeds of cats (including Ragdolls, Norwegian Forest, and Maine Coon cats).

Kehler, J.S., David, V.A., Schäffer, A.A., Bajema, K., Eizirik, E., Ryugo, D.K., Hannah, S.S., O’Brien, S.J., Menotti-Raymond, M.: Four independent mutations in the feline fibroblast growth factor 5 gene determine the long-haired phenotype in domestic cats. J Hered 98:555-66, 2007. Pubmed reference: 17767004. Doi: 10.1093/jhered/esm072.

Further information is available at the Online Mendelian Inheritance in Animals website.

Test #: C213

Cost: 60 € (excl. VAT)

Time: 7-10 days

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